Wednesday, November 30, 2011

Its Alive!

Its alive! Since June we have been working on a project to grow rat neurons in a multi-electrode array dish, which is like a petri dish but instrumented with electrodes so that you can record electrical activities from the cells. Over the summer we were pretty successful in growing the cells but we hadn't been able to make any good recordings.

Last week we scuttled the first batch of neurons and started a new batch, applying all of the hard earned knowledge from first time around. This time, victory! Just eight days after starting the neurons in the dish, we've made our first real recordings of neural activity. There are clear periods of spiking behavior and the spike waveforms are of the shape and amplitude that we expect. A real milestone for our lab!

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